Precision Equipment. Proven Expertise.
ExtruPharm combines advanced polymer processing equipment with hands-on expertise to deliver custom drug delivery devices that meet the most demanding project requirements.
ExtruPharm offers a comprehensive range of material processing equipment to accelerate the development of innovative drug delivery solutions. This equipment is configurable to produce the necessary attributes for manufacturing your specific pharmaceutical devices while still allowing for full transfer of processes to GMP facilities.
Precision Feeding, Dosing, and Pre-Processing for Material Consistency
Precision feeding, dosing, and pre-processing play a pivotal role in ensuring the quality, consistency, and efficiency of pharmaceutical manufacturing. Accurate material delivery supports uniform distribution of active ingredients, helping to achieve consistent content uniformity and therapeutic performance while safeguarding patient safety.
Our feeding and dosing systems along with proven manufacturing methods ensure consistent and precise material delivery including loss-in-weight twin-screw feeders for powders, loss-in-weight single-screw feeders for pellets, and liquid metering pumps for accurate liquid injection. Pre-processing capabilities include cryogenic polymer milling, along with sieving and blending to optimize particle size distribution and formulation uniformity.
Precision at the material input stage lays the foundation for high-quality, scalable, and cost-effective drug delivery solutions, making it a core element of modern pharmaceutical extrusion and continuous manufacturing strategies.
Advanced Twin-Screw and Single-Screw Extrusion Systems
Our extrusion suite features a range of twin-screw and single-screw systems designed to accommodate diverse formulation and processing needs. Twin-screw and Single-screw capabilities for precision processing. Specialized capabilities such as a melt pump, co-extrusion dies, rod, tube, and profile dies, film dies, and customer specific custom dies enable the production of complex geometries and multilayer structures with excellent dimensional control.
Comprehensive Secondary Processing and Prototyping Capabilities
ExtruPharm provides a full suite of services to streamline development and production. Our secondary processing capabilities include pelletizing, precision cutting, welding, laminating and injection molding to deliver the required attributes for your pharmaceutical devices.
These integrated capabilities help partners move efficiently from concept to commercialization, ensuring quality, speed, and innovation at every stage.
Custom Engineering & Design Solutions
Our custom engineering and design services enable us to tailor extrusion solutions to meet the unique technical requirements for each project.
Analytical, Testing
To support development and quality assurance, we maintain a comprehensive suite of analytical and testing tools, including in vitro dissolution testing to simulate in vivo release, UV-Vis spectroscopy for drug content analysis, HPLC for precise drug quantification, and particle size analysis for polymer and formulation optimization.
High Potency
- Standard and custom containment solutions for use with OEB 5 compounds
Extrusion Capabilities
- Twin-Screw Extruders: 18 mm Leistritz; Thermo MiniCTW conical twin; Xplore conical twin
- Single-Screw Extruders: AK system with 16 mm and 12 mm barrels; ¼” Randcastle system
- Specialized Capabilities: Melt pump; co-extrusion; rod, tube, profile; film
Feeding & Dosing Systems
- Loss-in-weight twin-screw feeder (powders)
- Loss-in-weight single-screw feeders (pellets)
- Volumetric single-screw feeders (pellets)
- Liquid metering pumps for precise liquid injection
Secondary Processing
- Injection Molding Machines: Nissi HM7 and ~5-10g/shot ram injection molding machine
- Pelletization and Micro-Pelletization
- Heated press
- Film Cutting: Pneumatic press and arbor press
- Welding and laminating for multi-layer and composite structures
Pre-Processing
- Cryogenic polymer milling
- Sieving and blending
Prototyping & Fabrication
- Film extrusion and die cutting for custom geometries
- Injection molding for implantable and parenteral devices
- Laser micrometers for high-precision dimensional control
Analytical & Testing Tools
- In vitro dissolution testing to simulate in vivo release
- UV-Vis spectroscopy for drug content analysis
- HPLC for accurate drug quantification
- Particle size analysis for polymer and formulation optimization
Custom Engineering & Design
Our capabilities extend beyond existing equipment. ExtruPharm can design, modify, or source custom tools and systems to meet the unique challenges of your program.